Spoilery triggers:
- Physical torture of various kinds. Tony, over the course of his tasks, deals with water-torture; self-inflicted wounds (he stabs himself in the throat so as to not drown, and later cuts a hole in the back of his head to remove a foreign object); multiple stab wounds by small metal barbs; multiple puncture wounds from contaminated needles; and his arc reactor is forcibly removed from his chest, causing him to go into cardiac arrest. He dies, technically, though only for a very short time.
-Multiple character deaths: These all refer to smaller characters, original characters that have been placed in the test area with Tony. He doesn't kill any of them; they all die because of one of Jigsaw's tests, though their deaths are graphically described.
- Trauma: Much of the story deals with the physical and emotional aftermath of Tony's experience, and as such, there are graphic descriptions of panic attacks, periods of dissociation, symptoms of PTSD. We also view this from Clint's perspective, so the story also focuses on Clint's own trauma and his aftermath.
- Serious illness: As a consequence of being (forcibly) injected by contaminated needles, Tony contracts Acute Hepatitis C, a serious and infectious illness. Though it is dealt with and the reactions are showed, the illness is resolved through medications and time, and it is not in the forefront of the story.